Man who had COVID-19 for 400 days was finally cured after being treated with antibodies, study finds

Man who had COVID-19 for 400 days was finally cured after being treated with antibodies, study finds

Rapid test device for COVID-19.Massimiliano Finzi/Getty Images

  • A man carried COVID-19 for more than 400 days.

  • The man had mild symptoms, so he was not initially eligible for anti-COVID-19 treatments.

  • Doctors eventually cured him using anti-COVID-19 antibodies.

A man who had COVID-19 non-stop for more than 400 days was finally cured, a study reporting the case said.

The man, 59, had a weakened immune system due to a recent kidney transplant. He first tested positive in December 2020 and carried the virus for at least 411 days, The Washington Post reported Nov. 4.

Genomic testing of the virus showed the man had the same strain of COVID-19 since his infection began, rather than picking up new variants from others.

“Nowadays everyone is infected with omicron, but when we looked at his virus, it was something that existed a long time ago,” Luke Blagdon Snell, a doctor who studies the evolution of viruses in Guy’s and St Thomas’ NHS Foundation Trust in the UK, told the Post.

“It was one of those old, early variants of the start of the pandemic,” he said.

The patient was paucisymptomatic, meaning he did not have the typical symptoms of COVID-19, such as cough, fever or loss of smell. Instead, he had other mild symptoms, Snell told Insider in an email.

Because his symptoms were mostly mild, he originally did not meet the criteria for accessing anti-COVID-19 treatments like antivirals or antibodies, which were reserved for more severe cases.

But doctors finally managed to cure the patient by giving him anti-COVID-19 antibodies in February 2022. The case was reported in the peer-reviewed journal Clinical Infectious Diseases on November 3.

Although the patient’s case is typically long, it is not the longest infection ever reported for COVID-19.

In April 2022, the same team reported the case of a patient who had COVID-19 for 505 days before his deathwhich was the longest documented case at the time, Snell told Insider.

Patients with these types of long-lasting COVID-19 infections tend to have caught the virus at a time when their immune system was weakened. These patients carry the virus continuously, unlike long-term covid patients who clear the infection early but may have lasting symptoms of the disease.

The scientists examined the patients because the virus may be able to mutate inside their body during such a long infection.

In another case, reported in June 2021, the virus mutated more than 30 times in a patient whose immune system was weakened by HIV.

Read the original article at Business Intern

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